{"id":984,"date":"2025-03-10T00:00:00","date_gmt":"2025-03-10T00:00:00","guid":{"rendered":"https:\/\/www.lunit.io\/media-hub\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\/"},"modified":"2025-03-10T00:00:00","modified_gmt":"2025-03-10T00:00:00","slug":"worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection","status":"publish","type":"media-hub","link":"https:\/\/www.lunit.io\/en\/media-hub\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\/","title":{"rendered":"World\u2019s First Large-Scale, Multicenter Prospective Study in Single-Reading Mammography Confirms Lunit AI Boosts Cancer Detection"},"content":{"rendered":"<ul>\n<li>\n<p>Prospective study finds Lunit AI increases cancer detection by 13.8% in single-reader settings without raising recall rates, presenting a game-changing tool for countries relying on single-reader mammography screening<\/p>\n<p><\/p>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" src=\"\/en\/wp-content\/uploads\/EDITOR\/241f7099-5e6e-498b-affa-0f6fdf63f5b5.jpg#2155\"><\/p>\n<p><\/p>\n<p>SEOUL, South Korea, March 10, 2025\u2014 Lunit (KRX:328130.KQ), a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today announced the publication of a <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-57469-3\" target=\"_blank\">groundbreaking prospective study in <em>Nature Communications<\/em><\/a>validating the real-world effectiveness of AI-powered mammography screening in South Korea\u2019s national breast cancer screening program. Conducted as the world\u2019s first large-scale, multicenter prospective study in a single-reading setting, the research underscores how AI-assisted mammography interpretation significantly improves breast cancer detection rates without increasing recall rates.<\/p>\n<p>The study was led by Professor Yun-Woo Chang from Soonchunhyang University Seoul Hospital, in collaboration with both breast and general radiologists from six leading academic hospitals in South Korea. The study analyzed 24,543 women aged 40 and above who underwent routine biennial mammography (2D full-field digital mammogram) between February 2021 and December 2022 as part of Korea's national breast cancer screening program.<\/p>\n<p>The study compared the performance of breast radiologists interpreting screening mammograms with and without Lunit's AI-based computer-aided detection, Lunit INSIGHT MMG. The results revealed that AI-assisted breast radiologists detected 13.8% more screen-detected breast cancers than those relying solely on conventional interpretation methods, or without AI assistance. The cancer detection rate (CDR) increased from 5.01 (per 1,000) to 5.70 with AI assistance, while recall rates (RRs) remained statistically unchanged, ensuring improved clinical effectiveness and minimizing unnecessary additional recalls. Moreover, AI assistance led to a significant improvement in detecting small-sized tumors and node-negative cancers, key indicators of improved early detection.<\/p>\n<p>Additionally, the study evaluated Lunit INSIGHT MMG\u2019s impact on general radiologists who do not specialize in breast imaging through a simulated retrospective study. The results demonstrated that AI assistance led to an even greater improvement in CDRs for general radiologists, with an increase of 26.4% (3.87 to 4.89 per 1,000), underscoring AI\u2019s potential to support radiologists with varying levels of expertise.<\/p>\n<p>\u201cThis prospective study offers compelling real-world evidence that AI can improve early cancer detection while maintaining effectiveness and reducing unnecessary patient anxiety caused by false positives in a single-reading setting,\u201d said Professor Chang, the lead and corresponding author of the study.<\/p>\n<p><strong>A Proven Solution for Single and Double-Reading Screening Systems<\/strong><\/p>\n<p>The publication further builds upon Lunit INSIGHT MMG\u2019s well-established track record in improving breast cancer detection. In Sweden, Capio St. G\u00f6ran Hospital conducted a prospective clinical trial to assess Lunit AI\u2019s effectiveness in breast cancer screening when replacing one reader within a double-reading setting. Following positive trial results, Capio St. G\u00f6ran Hospital became the world\u2019s first to replace one of two radiologists in its double-reading workflow with AI, marking a paradigm shift in breast cancer screening.<\/p>\n<p>\u201cThis latest prospective study in South Korea further solidifies Lunit INSIGHT MMG\u2019s potential as an indispensable tool in breast cancer screening,\u201d said Brandon Suh, CEO of Lunit. \u201cWhether in a single-reader or double-reader setting, AI can serve as a powerful force multiplier, assisting radiologists in detecting cancer earlier and more accurately.\u201d<\/p>\n<p><strong>Shaping the Future of National Breast Cancer Screening Programs<\/strong><\/p>\n<p>With mounting evidence supporting AI\u2019s role in breast cancer screening, Lunit is driving its global adoption. Lunit INSIGHT MMG has already been deployed in national breast screening programs in Australia, Sweden, Iceland, Singapore, Saudi Arabia, and Qatar, helping healthcare systems enhance efficiency and optimize diagnostic accuracy.<\/p>\n<p>The study\u2019s findings are expected to influence global breast cancer screening protocols, particularly in countries where single-reading mammography interpretation is widely practiced. By demonstrating AI\u2019s ability to enhance radiologists\u2019 accuracy without increasing RRs, the study provides critical data supporting AI\u2019s role in optimizing cancer detection while reducing the workload burden on radiologists. This is particularly relevant as many countries face a shortage of specialized breast imaging professionals, making AI an important tool to improve efficiency and maintain high diagnostic standards.<\/p>\n<p>\u201cAs AI adoption accelerates, we remain committed to driving innovation and making AI-powered cancer screening the new standard of care,\u201d added Suh. \u201cBy working closely with healthcare providers worldwide, we aim to ensure that AI benefits as many patients as possible.\u201d<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"template":"","media-hub-type":[36],"class_list":["post-984","media-hub","type-media-hub","status-publish","hentry","media-hub-type-cancer-screening"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>World\u2019s First Large-Scale, Multicenter Prospective Study in Single-Reading Mammography Confirms Lunit AI Boosts Cancer Detection - Lunit<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lunit.io\/en\/media-hub\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"World\u2019s First Large-Scale, Multicenter Prospective Study in Single-Reading Mammography Confirms Lunit AI Boosts Cancer Detection - Lunit\" \/>\n<meta property=\"og:description\" content=\"Prospective study finds Lunit AI increases cancer detection by 13.8% in single-reader settings without raising recall rates, presenting a game-changing tool for countries relying on single-reader mammography screening SEOUL, South Korea, March 10, 2025\u2014 Lunit (KRX:328130.KQ), a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today announced the publication of a groundbreaking prospective [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.lunit.io\/en\/media-hub\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\/\" \/>\n<meta property=\"og:site_name\" content=\"Lunit\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@lunit_ai\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.lunit.io\\\/en\\\/media-hub\\\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\\\/\",\"url\":\"https:\\\/\\\/www.lunit.io\\\/en\\\/media-hub\\\/worlds-first-large-scale-multicenter-prospective-study-in-single-reading-mammography-confirms-lunit-ai-boosts-cancer-detection\\\/\",\"name\":\"World\u2019s First Large-Scale, Multicenter Prospective Study in Single-Reading Mammography Confirms Lunit AI Boosts Cancer Detection - 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